ET has learned that JAMES VAN DER BEEK will guest star on an October episode of “Ugly Betty.”

The former “Dawson’s Creek” star will play one of Mode magazine’s top advertisers who pressures Daniel Meade (ERIC MABIUS) to fire his transsexual sister, Alexis (REBECCA ROMIJN), because he doesn’t want to do business with her.

No word yet on whether or not Van Der Beek will have any scenes with Betty (AMERICA FERRERA).

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