Jessica Biel, 28, says one of her toughest life decisions was to leave college to pursue her acting career.

“I do still have a desire, a pang in my heart, when I think about it and the fact that I didn’t spend my four years with my friends,” Biel said.

“I didn’t stay with my friend Hayden in our apartment—I bailed and she ended up living with some random people. I still feel bad. But then again, I’ve had wonderful experiences.”

It looks like her decision was the right one. Biel has had a very successful career and will be starring in The A-Team with Bradley Cooper.

She is best known for her role as Mary on the tv series 7th Heaven and for her relationship with singer/actor Justin Timberlake.

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Justin Timberlake and Jessica Biel’s notoriously on-and-off relationship is once again on the rocks as the singer cozies up to ex Cameron Diaz while shooting the romantic comedy Bad Teacher, reports the new Us Weekly (on newsstands now).

Multiple sources tell Us Weekly that Diaz, 37, and Timberlake, 29, flirt openly on the Valencia, Calif., set.

“He tortured Jess by taking this role, and they are reaching a breaking point,” a pal tells Us Weekly. “The truth is, I don’t know if they can survive this.”

While shooting, it’s like “old times” for Timberlake and Diaz, who dated for four years before he began romancing Biel, 28, in 2007.

There’s “lots of laughing, making fun of each other, kidding around off camera,” the source says. “She’s sassy with him — and slick, prancing around in tight clothes.”

Biel and Timberlake have been having “huge arguments” on the phone about it, says one source. The more Biel gets “territorial and upset,” another adds, Timberlake gets turned off and turns more toward Diaz, with whom he has been having “a ball.”

And though Timberlake’s mom has told Us that Biel is “one of us,” a source close to Timberlake tells Us Weekly he “won’t marry” her because “he doesn’t respect her anymore.” In fact, the source says, “when she’s not around, he’ll make fun of her to his friends.”

For more – including just how badly things changed between Biel and Timberlake after he took the role opposite Diaz; Diaz and Timberlake’s cozy on-set lunch dates; the cruel “mind games” Timberlake plays on Biel; how Biel thinks Diaz is an “evil bitch” and why Biel stays with Timberlake even though she “knows he flirts with other women” – pick up the new Us Weekly today!

Tell Us: Do you like Justin better with Jessica or Cameron?

Source, Fame Pictures

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Both Cameron Diaz and Justin Timberlake looked in great spirits as they teamed up for the day’s shoot on set of Bad Teacher in Los Angeles, Ca on March 21, 2010. Much hype surrounds the reunion between the two former lovers and all eyes will be on how the two will interact and potentially reignite romantic flames while filming.

Fame Pictures