Last night hottie Ryan Reynolds made a special guest appearance on “Jimmy Kimmel Live!” where he was asked to do the late-night host a favor and fire a staffer who is a huge fan of the actor. Check out the video above to see how Ryan handled the awkward situation that Kimmel put him in.

Last night on “Jimmy Kimmel Live!” hip-hop star Drake stopped by to chat with Jimmy and premiere the music video to his recent collaboration with the late-night host, the “Twitter-Rap.”

“Watching Lost is what I imagine it must be like to be trapped inside the brain of Paula Abdul.”

– Jimmy Kimmel, at ABC’s upfront presentation of its new fall schedule

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Tracy Morgan teamed up with late-night host Jimmy Kimmel for a music video titled “Impregn8ed” that aired tonight on “Jimmy Kimmel Live” on ABC at 12:05 am ET/PT.

Love both of them – so funny!

Round Two!

Jay Leno told Oprah Winfrey on Thursday that he felt “sucker-punched” by Jimmy Kimmel – and hours later, the ABC comedian came out swinging again.

“[Leno] went on Oprah and rats me out,” Kimmel said during his Jimmy Kimmel Live! monologue Thursday night. “That’s a sucker-punch right there. You don’t go to Oprah and say that. He’s a tattle-tale.”

Kimmel added: “Oprah and I had a wonderful relationship, and now it’s ruined because of Jay.” (Click here to see Kimmel’s monologue.)

Kimmel, of course, was kidding. But in his sharp five-minute monologue, the comedian defended his recent appearance on The Jay Leno Show in which he let loose about shakeups at NBC that ultimately led to Leno reclaiming his post as the host of The Tonight Show and ousting Conan O’Brien in the process.

Explaining that Leno’s producers called him in advance to discuss the questions for the “10@10″ segment, Kimmel says that he expected to be commenting on the late-night controversy, since it was newsy – and funny to him. Instead, Leno wanted to chat about other things like, Kimmel said, “What’s your junk food weakness?”

“I figured I’d start in, he’d get into it and we’d mix it up,” Kimmel said. “You know, at one time [Leno] was a comedian. But he didn’t do that. He stood there and he just kind of read through the questions like a robot.”

For his part, Leno told Winfrey that he was taken aback by Kimmel’s remarks but ultimately decided not to edit them out of his show. “I said, ‘No. Put it out there. I walked into it,’ ” Leno told her, explaining that when you get hit, “You get right up again. You don’t whine and complain.”

But at the end of his monologue Thursday night, Kimmel had the last laugh – for now. “Watch out Oprah,” he said, “don’t think he won’t take your show next.”

Source, Fame Pictures

Last night on ABC’s “Jimmy Kimmel Live,” comedian Kathy Griffin joined the late-night host to chat about her autobiography “Official Book Club Selection: A Memoir According to Kathy Griffin” (which she claims is going to “out-sell The Bible”) as well as share a clip of her newest role as “Jon & Kate Plus 8” mother Kate Gosselin.

“It’s like my ‘Malcolm X’,” joked Griffin.

Check out the exclusive trailer to the Jimmy Kimmel Live! biopic “Kate is Enough: The Kate Gosselin Story” in which Kathy stars alongside George Takei as Jon Gosselin.

It is sooooooooo funny.

On last night’s Jimmy Kimmel, Kimmel and guest Matthew Fox had a staring contest to see who would claim the title of “Gorgeous Man” and ended up in the shower together.

I really should watch the Kimmel show, he cracks me up. Sorry I missed Matthew Fox last night!

Did you guys watch the Lost finale? I just finished it a couple minutes ago, and holy crap! The first hour and a half were pretty boring, but man – the last half hour was INTENSE!! So excited to see what they do next season (which is the last season!)