Photocall of Marley and Me with Jennifer Aniston and Owen Wilson
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George Clooney will be back in his ER scrubs for one final episode of the NBC medical drama that will air March 12.
A show insider tells PEOPLE that Clooney will reunite with Julianna Margulies in a storyline that also features Susan Sarandon, making her ER debut as a grandmother grief-stricken over the sudden death of her grandson.
Although execs of Warner Brothers and NBC have been coy about Clooney’s return, ER’s executive producer John Wells did tell PEOPLE on Wednesday that the March 12 episode will be a memorable one.
“If you’re a fan of ER, you won’t want to miss this one,” said Wells, stopping short of naming the main attraction, Clooney as Dr. Doug Ross.
The episode brings Clooney’s character back to his longtime love Margulies’ nurse Carol Hathaway. Will the star-crossed pair finally get their happy ending?
Wells, who wrote the series’ final episodes, would say only, “I want their story to be very fulfilling in the end.”
Clooney, 47, left ER in 1999 for roles on the big screen. Margulies, 42, who exited the series the following year, recently welcomed her first child Kieran, with husband, attorney Keith Lieberthal.
The show began shooting its two-hour final episode this week. Its series finale will air April 2.

Gwyneth Paltrow is taking on critics of her lifestyle Web site, Goop.com, just days after The New York Times published an article questioning the site’s relevance in light of a barrage of published swipes against its cardio-workout and pizza-recipe content. Also under attack: the site’s perceived omniscient tone.
“I think the people who are criticizing it or criticizing the idea of it, don’t really get it, because if they did, they would like it,” Paltrow, 36, told PEOPLE Wednesday night at a New York City benefit she hosted for Bent On Learning, a non-profit organization which arranges yoga and meditation classes in the city’s public schools.
Yet as The Times noted, “many critics find the enterprise fatuous and a bit puzzling.” Typical is a query from Toronto’s The Globe and Mail: “Why is it called Goop?” its writer asked. “Perhaps ‘Any Old Load of Rubbish’ and ‘Learn From Me, Ungrateful Peasant’ were both taken.”
Paltrow said she believes some of the barbs simply stem from the fact that she’s doing something new and different. “I think that people like people to stay in their ‘box’ – they like people to stay how they are comfortable seeing them.”
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In Touch can exclusively reveal that Rihanna has not pressed charges against her alleged attacker, Chris Brown, as of now. “We do not have enough evidence and there have been no charges filed on the Chris Brown case,” a spokesperson in the Los Angeles DA’s office tells In Touch.
But Chris is not necessarily out of hot water, even if Rihanna never files charges. “If the state gathers up enough evidence, we will press charges with or without her testifying. It is not up to the victim.”
With a March 5 arraignment date set in LA for Chris, 19, In Touch has also learned that Rihanna does not have to make an appearance at the courthouse. “She will not have to show up during the arraignment,” the spokesperson says. The only way Rihanna, 21, will be forced to face Chris is if the case, which remains under investigation, goes to trial.

As the former wife of McDreamy, Addison Montgomery is maybe the most famous divorcee on national television.
But Kate Walsh, the woman who plays her on both Grey’s Anatomy and its spin-off Private Practice, never imagined that she would have to go through the same ordeal off-screen.
“I don’t think anyone gets married thinking that they will get divorced,” says Walsh, 41, opening up about her divorce from film studio executive Alex Young, 38, for the first time in next month’s Redbook cover story.
Walsh adds: “Alex and I still care for each other, and I wish him nothing but the best.”
And the actress gave praise to the people who stepped up to comfort and support her during the difficult time.
“The silver lining to this, however, is that I have a wonderful family and a great group of friends who really showed their support and encouragement, and for that I am truly grateful,” she says.
In December, Young filed for divorce after 15 months of marriage citing irreconcilable differences. The couple had tied the knot last September after a three-month courtship.
“I second-guess myself all the time,” Walsh told the magazine. “I make a decision and then wonder if I made the wrong choice. Sometimes I come off as confident, but really I am a quivering little wharf rat underneath.”
Right now she is a wharf rat in need of a date. Walsh admitted to Redbook that her favorite form of courtship – calling a guy and then hanging up when he picks up – has been made obsolete in the age of caller ID.
“Remember when you could mildly stalk a guy?” mused Walsh. “Not anymore, man. They can be at your front door in five minutes. There’s just no mystery now.”
